CHE 490 Fundamentals of Biochemical Engineering
Credit Structure :(3-0)3
Catalog Description :
Comparison
of chemical and biochemical engineering; bioprocesses; microorganism as the microbioreactors; biomolecules; cellular growth reactions; enzyme kinetics and immobilization; bioreactors, and transport phenomena
in bioreactors.
Course Objectives :
To give the basic principles
of biochemical engineering;
an understanding of the impact of biochemical engineering in a global and environmental context, consistent with the principles of sustainable development; a familiarity with the contemporary biochemical engineering issues; abilities to communicate effectively; a solid understanding of professional and ethical responsibility;
an awareness of the need for, and
ability to engage life-long learning.
Prerequisites :
None
Text Book :
J.E. Bailey,
F.Ollis 1986. "Biochemical
Engineering Fundamentals", McGraw
Hill, 2nd edition, New
York.
Reference:
H.W. Blanch and D.S. Clark, 1997. “Biochemical Engineering”, Mercel Dekker Inc, New Yrok.
Doran,
P.M., 1995. “Bioprocess Engineering
Principles”, Academic
Press, San Diego.
Syllabus :
Introduction:
Chemical Engineering and Biochemical Engineering, Opportunities in Industrial Biotechnology, Bioprocesses
(1 week).
Microorganisms
as Microbioreactors : Structure
of cells, Important industrial cell types, Cell culturing techniques (1 week)
Biomolecules:
Macromolecules and their monomers; Enzymes (1 week)
Cell Growth Reactions : Liquid cell transport
processes; Intracellular reactions; Biosynthesis and polymerization reactions
of biomolecules
(1.5 weeks)
Bioreactors (1 week)
Enzyme Kinetics and Enzyme
Catalyzed Reactions : Enzyme Kinetics, Enzyme inhibition; Enzyme immobilization
(1.5 weeks)
Kinetics
of Substrate Utilization, Product Formation, and Biomass Production (1.5 weeks)
Transport
Phenomena in Bioreactor Systems (1.5 weeks)
Industrial
Bioprocesses (Student oral presentations: project topics) (3 weeks)
Midterm
Exams (1 week)
Homeworks, Quizzes, Projects:
Term project and monthly homeworks are given
Computer
Usage:
Term project preparation and presentation
Laboratory work:
None
Category Content:
Mathematics
and Basic Sciences: 0.5 credits
Engineering
Sciences: None
Humanities
& Social Sciences: None
Departmental:2.5
credits
Instructors:
Ufuk Bakır, Pınar Çalık
Credit Structure :(3-0)3
Catalog Description :
Review of basic biological concepts such as cell construction,
cell nutrients, and enzyme kinetics.
Large scale production of enzymes. Selection of bioreactors. Recovery and purification
of products.
Course Objectives :
The purpose of this course is to introduce the
essential concepts of biochemical engineering to chemical engineering
students which they can apply to biological systems.
Prerequisites :
None
Text Book
:
M.L. Shuler, F. Kargi,
"Bioprocess Engineering,
Basic Concepts", Prentice Hall, 1992
Reference:
J.E. Bailey, F.Ollis "Biochemical Engineering
Fundamentals", McGraw Hill,
1986
A.H. Scragg, "Biotechnology
for Engineers", John Wiley and Sons,
1988
Syllabus :
Introduction (1 week).
Essential Biochemistry (2 weeks)
Enzymes and Microorganisms (2.5 weeks)
Microbial Growth and Product Formation
(2.5 weeks)
Biological Reactors (3 weeks)
Media Preparation and Sterilization (1 week)
Biological Separation (2 weeks)
Homeworks, Quizzes, Projects:
Monthy homeworks are given
Computer Usage:
None
Laboratory work:
None
Category Content:
Mathematics and
Basic Sciences: 2.5 credits
Engineering Design:
None
Engineering Sciences:
0.5 credit
Humanities & Social
Sciences: None
Departmental:None
Instructors:
Staff